Are approved to treat ED Can be effective: Regardless of age For mild, moderate, or severe ED In men with health problems such as diabetes or controlled high blood pressure Do not need to be planned around meals Should not be taken if drinking too much alcohol (for example, 5 glasses of wine or 5 shots of whiskey) This may cause headache or dizziness, increase in heart rate, or drop in blood pressure Should not be taken with medicines called “nitrates” or recreational drugs known as “poppers,” or with medicines called “guanylate cyclase stimulators,” such as riociguat (Adempas®)|| The combination can cause a sudden, unsafe drop in blood pressure Should not be taken with other ED medicines Should not be taken more than one time each day